ASM Poster Presentation Australian Society for Microbiology Annual Scientific Meeting 2025

Investigating outer domain redundancy of the bacterial flagellar filament (#254)

Jacob Scadden 1 , Pietro Ridone 1 , Divyangi Pandit 1 , Yoshiyuki Sowa 2 3 , Matt AB Baker 1
  1. University of New South Wales, Sydney, NSW, Australia
  2. Department of Frontier Bioscience, Hosei University, Tokyo, Japan
  3. Research Center for Micro-Nano Technology, Hosei University, Tokyo, Japan
Publish consent withheld
  1. Kang, X et al. “Amino acids 89-96 of Salmonella flagellin: a key site for its adjuvant effect independent of the TLR5 signaling pathway.” Cellular & molecular immunology vol. 14,12 (2017): 1023-1025.
  2. Biedma, ME et al. “Recombinant flagellins with deletions in domains D1, D2, and D3: Characterization as novel immunoadjuvants.” Vaccine vol. 37,4 (2019): 652-663.
  3. Kreutzberger, M.A.B., Sobe, R.C., Sauder, A.B. et al. Flagellin outer domain dimerization modulates motility in pathogenic and soil bacteria from viscous environments. Nat Commun 13, 1422 (2022)
  4. Wang, F. et al. A structural model of flagellar filament switching across multiple bacterial species. Nat. Commun. 8, 960 (2017).
  5. Scadden, J., et al. Rescue of bacterial motility using two and three-species FliC chimeras. bioRxiv 2024.12.02.626473 (Currently in review at Journal of Bacteriology).